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Table 3 Adverse events in both groups. The treatment (CXL) group showed significantly more haze and corneal erosion during the follow-up period. After 3 years, all but 3 eyes showed a complete resolution of the haze

From: Prospective, randomized, double-blind trial to investigate the efficacy and safety of corneal cross-linking to halt the progression of keratoconus

  

Placebo group

CXL group

 

Maximal haze

0

71 % (10)

0 % (0)

p < 0.01

1

7 % (1)

20 % (3)

 

2

21 % (3)

73 % (11)

 

3

0 % (0)

7 % (1)

 

Corneal erosions

0

79 % (11)

7 % (1)

p < 0.01

1

0 % (0)

7 % (1)

 

2

7 % (1)

13 % (2)

 

3

7 % (1)

60 % (9)

 

4

7 % (1)

13 % (2)