Table 8 Summary of AGV compared to BGI for glaucoma
From: Comparison of the Ahmed glaucoma valve with the Baerveldt glaucoma implant: a meta-analysis
Outcomes | No of participants (studies) follow up | Quality of the evidence (GRADE) | Relative effect (95 % CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
Risk with BGI | Risk difference with AGV (95 % CI) | ||||
IOP (short-term) | 685 (6 studies) 12 months | ⊕⊝⊝⊝ VERY LOW1 due to inconsistency | The mean iop (short-term) in the intervention groups was 2.12 higher (0.72 to 3.52 higher) | ||
IOP (long-term) | 659 (7 studies) 20 to 60 months | ⊕⊝⊝⊝ VERY LOW2 due to inconsistency | The mean iop (long-term) in the intervention groups was 1.85 higher (0.43 to 3.28 higher) | ||
Success rate (short-term) | 714 (5 studies) 12 months | ⊕ ⊕ ⊝⊝ LOW | OR 0.97 (0.56 to 1.66) | 797 per 1000 | 5 fewer per 1000 (from 110 fewer to 70 more) |
Success rate (long-term) | 835 (7 studies) 20 to 60 months | ⊕ ⊕ ⊝⊝ LOW | OR 0.73 (0.54 to 0.99) | 684 per 1000 | 72 fewer per 1000 (from 2 fewer to 145 fewer) |
Medication (short-term) | 558 (3 studies) 12 months | ⊕ ⊕ ⊝⊝ LOW | The mean medication (short-term) in the intervention groups was 0.29 higher (0.07 to 0.5 higher) | ||
Scale from: 0 to 5. | |||||
Medication (long-term) | 659 (7 studies) 20 to 60 months | ⊕ ⊕ ⊝⊝ LOW | The mean medication (long-term) in the intervention groups was 0.42 higher (0.22 to 0.62 higher) | ||
Scale from: 0 to 5. | |||||
Total complications | 971 (8 studies) 1 to 3 years | ⊕ ⊕ ⊝⊝ LOW | OR 0.67 (0.5 to 0.9) | 377 per 1000 | 89 fewer per 1000 (from 24 fewer to 145 fewer) |
Servere complications | 971 (8 studies) 1 to 3 years | ⊕ ⊕ ⊝⊝ LOW | OR 0.57 (0.36 to 0.91) | 110 per 1000 | 44 fewer per 1000 (from 9 fewer to 67 fewer) |
Reoperation for glaucoma | 632 (3 studies) 3 to 5 years | ⊕ ⊕ ⊝⊝ LOW | OR 2.7 (1.54 to 4.74) | 60 per 1000 | 87 more per 1000 (from 29 more to 172 more) |
Hypotony | 724 (6 studies) 1 to 3 years | ⊕ ⊕ ⊝⊝ LOW | OR 0.54 (0.26 to 1.11) | 83 per 1000 | 37 fewer per 1000 (from 60 fewer to 8 more) |
Tube complications | 620 (4 studies) 1 to 3 years | ⊕⊝⊝⊝ VERY LOW3 due to inconsistency | OR 0.68 (0.25 to 1.87) | 132 per 1000 | 38 fewer per 1000 (from 95 fewer to 89 more) |
Hyphema | 620 (4 studies) 1 to 3 years | ⊕ ⊕ ⊝⊝ LOW | OR 0.64 (0.36 to 1.13) | 109 per 1000 | 36 fewer per 1000 (from 67 fewer to 12 more) |
Choroidal effusion | 693 (5 studies) 13 to 36 months | ⊕ ⊕ ⊝⊝ LOW | OR 1.1 (0.72 to 1.69) | 106 per 1000 | 11 more per 1000 (from 30 fewer to 73 more) |