Fig. 2

The affected family members’ corneal phenotype illustrating TBCD as shown by slit-lamp examination. Note the tiny superficial opacities of the proband’ daughter (IV:4), bilateral irregular corneal surfaces, multiple discrete, dense gray-white, honeycomb-shaped opacities in a geographic distribution of the proband (III:5), and extensive honeycomb-shaped configuration of grayish opacities beneath the epithelium and at the Bowman’s layer of the proband’s brother (III:1). Clear area appears around the corneoscleral limbus in all the patients. These images are published with the consent of the patients, and in the case of the 6-year old patient, with the consent of her parents