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Table 1 Characteristics and quality assessment of the included studies

From: Association between a vascular endothelial growth factor gene polymorphism (rs2146323) and diabetic retinopathy: a meta-analysis

Author

Year

Ethnicity

Country

N

Diabetes

Duration of diabetes (DR/DWR), years

Male (DR/DWR), %

HbA1c (DR/DWR), %

Genotype typing

NOS

Yang XF [22]

2014

Asian

China

490

Type 2

15 ± 5 / 13 ± 7

0.45 / 0.39

7.8 ± 1.7 / 7.0 ± 1.4

PCR-RFLP

5

Kangas-Kontio T [21]

2009

Caucasian

Finland

224

Type 1/2

24 ± 10 / 25 ± 7

0.60 / 0.51

Not reported

RT-PCR/Taqman

6

Abhary S [19]

2009

Caucasian

Australia

487

Type 1

31 ± 13 / 15 ± 9

0.39 / 0.48

8.8 ± 2.3 / 7.6 ± 2.5

Mass spectrometer

5

     

Type 2

18 ± 9 / 13 ± 9

0.56 / 0.65

7.5 ± 3.4 / 6.6 ± 2.9

  

Churchil AJ [20]

2008

Caucasian

UK

106

Type 1/2

23 / 25

0.60 / 0.52

Not reported

PCR-RFLP

5

  1. DR diabetes with retinopathy, DWR diabetes without retinopathy, PCR RFLP PCR with restriction fragment length polymorphism, HWE Hardy-Weinberg equilibrium, NOS The Newcastle–Ottawa Scale [23]. Values are the mean ± standard deviation, where appropriate