Table 1 main clinical features, locations of the involvements, imaging manifestation, and therapeutic data of the cases

Cases

11

Mean age (range)

53.7 (45–60)

Gender(F/M)

3/8

Accompanying disease

 Diabetes mellitus

9

 Renal transplant

1

 Trauma

1

Locations of the involvements

 Rhinocerebral

11

 Sino-orbital

0

 Rhino-orbital-cerebral

11

Clinical involvement

 Orbital apex syndrome

11

Imaging manifestation(CT/MRI)

 Thickening in sinus Mucosa

11

 Inflammation in the periorbital muscles

11

 Involvement of the cavernous sinus

4

 Occlusion of the internal carotid artery

2

 Sings of cerebral infarct

2

Rhinoscopy

11

Therapy

 Surgical debridement

8

 Amphotericin B.

11

Outcomes

 Survive with sequeale

3

 Death

8