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Table 4 Genes up-regulated in endothelium of mice dysfunctional corneal allografts relative to syngenic control as detected by PCR array

From: Oxidative stress and premature senescence in corneal endothelium following penetrating keratoplasty in an animal model

Gene description

Symbol

Fold regulation

P

Antioxidant

   

Glutathione Peroxidases (Gpx)

   

 Glutathione peroxidase 3

Gpx3

1.17

0.0118

Other Peroxidases

   

 Glutathione reductase

Gsr

1.25

0.0079

 Catalase

Cat

1.24

0.0033

 Adenomatosis polyposis coli

Apc

1.11

0.0144

 Peroxiredoxin 6, pseudogene 1

Prdx6-ps1

1.17

0.0051

 Tropomodulin 1

Tmod1

1.37

0.0004

ROS Metabolism

   

Superoxide Metabolism

   

 Stearoyl-Coenzyme A desaturase 1

Scd1

1.09

0.0385

Oxidative stress responsive genes

   

 Isocitrate dehydrogenase 1 (NADP+), soluble

Idh1

1.19

0.0016

 Protein phosphatase 1, regulatory (inhibitor) subunit 15b

Ppp1r15b

1.22

0.0048

 Peroxiredoxin 2

Prdx2

1.29

0.0114

Oxygen transporters

   

 Solute carrier family 38, member 1

Slc38a1

1.11

0.0462