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Table 1 Comparison with control group

From: Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases

Response Drug Dose Mean SD P
MMP-1 B 10 1.9 0.4 0.044
B 100 5.0 0.6 <0.001
B 1000 8.4 0.6 <0.001
L 10 2.0 0.5 0.018
L 100 2.7 0.4 <0.001
L 1000 7.8 0.7 <0.001
T 10 3.0 0.3 0.273
T 100 4.6 2.9 0.023
T 1000 11.2 2.3 <0.001
MMP-2 B 10 7.5 0.6 0.501
B 100 23.1 4.5 0.002
B 1000 92.5 14.2 <0.001
L 10 5.5 0.6 0.100
L 100 12.7 3.4 <0.001
L 1000 41.2 5.2 <0.001
T 10 3.6 0.6 0.706
T 100 14.4 3.0 <0.001
T 1000 30.5 6.4 <0.001
MMP-3 B 10 8.9 0.9 1.000
B 100 14.9 3.8 0.604
B 1000 234.0 34.7 <0.001
L 10 4.2 0.8 1.000
L 100 6.1 0.7 0.432
L 1000 69.8 10.9 <0.001
T 10 11.4 2.2 0.030
T 100 31.6 5.8 <0.001
T 1000 63.3 9.2 <0.001
MMP-9 B 10 2.3 0.3 1.000
B 100 11.5 1.6 0.001
B 1000 45.8 5.7 <0.001
L 10 10.6 1.9 0.019
L 100 17.0 2.5 <0.001
L 1000 86.2 8.9 <0.001
T 10 6.5 0.6 <0.001
T 100 9.8 0.9 <0.001
T 1000 12.6 2.1 <0.001
MMP-17 B 10 3.9 2.2 1.000
B 100 63.2 13.4 0.006
B 1000 176.5 47.9 <0.001
L 10 2.3 1.1 1.000
L 100 4.9 1.7 1.000
L 1000 173.1 74.7 <0.001
T 10 4.8 1.7 0.105
T 100 8.8 1.7 0.002
T 1000 18.5 4.8 <0.001
TIMP-1 B 10 67.6 8.3 <0.001
B 100 49.8 6.7 <0.001
B 1000 39.2 5.2 <0.001
L 10 71.0 10.2 <0.001
L 100 61.3 11.9 <0.001
L 1000 31.3 6.5 <0.001
T 10 85.9 11.5 0.038
T 100 48.1 6.3 <0.001
T 1000 30.0 8.7 <0.001
TIMP-2 B 10 89.2 10.8 0.082
B 100 50.2 7.5 <0.001
B 1000 49.6 5.3 <0.001
L 10 66.7 11.6 <0.001
L 100 49.7 7.1 <0.001
L 1000 29.0 6.6 <0.001
T 10 72.2 9.1 <0.001
T 100 62.4 6.2 <0.001
T 1000 30.1 4.6 <0.001
  1. P one-way ANOVA with Bonferroni’s post hoc test for multiple comparisons
  2. B bimatoprost, L latanoprost, T tafluprost
  3. Dose: μM