1. A loss of VA ≥5 letters than the best VA recorded since baseline. |
2. New retinal haemorrhage. |
3. The presence of IRF or SRF on OCT. |
For patients in the Intensive retinal fluid arm, this criterion is “the presence of any IRF or SRF”. |
For patients in the Relaxed retinal fluid arm, this criterion is “the presence of any IRF or SRF >200 μm in height at subfoveal centre” (as measured by the caliper function on the OCT). Sub-RPE fluid does not constitute part of the decision-making criteria for either arm. |