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Fig. 1 | BMC Ophthalmology

Fig. 1

From: Angiogenin ameliorates corneal opacity and neovascularization via regulating immune response in corneal fibroblasts

Fig. 1

Comparison of corneal opacity and neovascularization in rat corneas with alkali burn between the angiogenin (ANG) group and the control group. a Representative photographs demonstrated the corneal surface on day 3 and 56 after injury. Marked corneal opacity (arrow) was noted by day 56 after injury, and significant neovascularization (arrow head) developed by day 56 after injury to the cornea in the control group. In contrast, the clear transparent cornea (inside large black circle) and clear papillary margin (small black circle) in the ANG-treated cornea is noted. b Quantification of corneal opacity following a clinical grading system on a scale from 0 to +4 and quantification of corneal neovascularization. Corneal opacity and neovascularization were significantly down-regulated by ANG administration. Quantified estimates of corneal neovascularization are expressed as relative ratio of the neovascularizaed area to the whole corneal area. Values represent the mean ± standard error. Mann–Whitney U test, *p < 0.05

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