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Table 1 Baseline characteristics and three-year outcomes during ranibizumab monotherapy [mean (SD)]

From: Retinal pigment epithelial atrophy over polypoidal choroidal vasculopathy lesions during ranibizumab monotherapy

 

All eyes (n = 100)

Baseline RPE atrophy in treated eye

Absent (n = 16)

Present (n = 84)

Age (years)

71.5 (9.5)

70.0 (8.9)

71.8 (9.7)

RPE atrophy area (mm2)

 Baseline

1.22 (1.72)

0

1.43 (1.80)

 Three years after the first IVR

2.91 (5.41)

0.55 (0.35)

3.36 (5.79)

 Change value

1.69 (5.04)

0.55 (0.35)

1.92 (5.47)

RPE atrophy area in fellow eyes (mm2)

 Baseline

0.93 (1.33)

0.02 (0.01)

1.09 (1.95)

 Three years after the first IVR

1.14 (1.69)

0.24 (0.60)

1.31 (2.24)

 Change value

0.22 (0.79)

0.22 (0.64)

0.22 (1.05)

Visual acuity (logMAR value)

 Baseline

0.33 (0.36)

0.31 (0.09)

0.33 (0.39)

 Three years after the first IVR

0.23 (0.31)

0.19 (0.22)

0.25 (0.32)

 Change value

0.10 (0.25)

0.12 (0.14)

0.08 (0.28)

PCV lesion area (mm2) at baseline

2.93 (1.60)

2.46 (0.99)

3.02 (1.68)

No. injections during three years

11.4 (4.50)

10.3 (3.51)

11.6 (4.82)

  1. SD standard deviation, RPE retinal pigment epithelium, logMAR logarithm of the minimum angle of resolution, IVR intravitreal injection of ranibizumab, PCV polypoidal choroidal vasculopathy