Fig. 2

Normal choroidal vasculature and choroidal neovascularization (CNV) showing by OCT angiograms. The normal appearance of the outer retina showed in absence of blood flow (a1). The normal appearance of the choroid capillary showed with homogeneous grayish capillary beds (a2). The early phase and the late phase of normal FA images were shown in (a5) and (a6) respectively. Hyperreflective CNVs were demonstrated at both the outer retina level (b1, c1) and the choroid capillary level (b2, c2). The configurations of these CNV lesions were strikingly identical with those in the early phase of FA (b5, c5). CNV was in a globular aspect in (b1) and (b2), while in a fan-like shape with a feeder vessel in (c1) and (c2). The hyporeflective speckles (white arrowheads, b2) regarding the hard exudates were “mirror images” projected from the deep retinal plexus layer (not shown). The early phase of FA (b5, c5) revealed hyperfluorescent CNVs, while the late phase of FA (b6, c6) showed leakage and edema caused by CNV. The double lines in B scan OCT images of a3, a4, b3, b4, c3, and c4 indicated the layers exhibited in a1, a2, b1, b2, c1, and c2 respectively. (Yellow dashed line: CNV; White arrow head: “mirror image” of hard exudate)