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Fig. 3 | BMC Ophthalmology

Fig. 3

From: Prospective clinical trial of Intravitreal aflibercept treatment for PolypoIdal choroidal vasculopathy with hemorrhage or exudation (EPIC study): 6 month results

Fig. 3

Resolution of a vascularized RPED after aflibercept therapy. a. An Asian male with a persistent large vascularized RPED after 24 months of high dose ranibizumab therapy (12 2.0 mg ranibizumab + 12 1.0 mg ranibizumab injections) in PEARL2 study at EPIC baseline (upper left). Resolution of the vascularized RPED which initially resolved at month 3 and stayed resolved at month 6 (upper right) b. Treatment naïve Caucasian female with vascularized RPED at EPIC baseline (left) and after aflibercept therapy at month 6 (right). Note the marked improvement in the vascularized RPED. c. Corresponding ICG angiogram to patient in B. Increased visibility of BVN after RPED resolution on aflibercept therapy. ICG angiogram shows hypofluorescence in the area of the RPED at baseline with inferior PCV complex (left). Follow-up ICG angiogram shows decreased hypofluorescence due to resolution of the RPED. Note the increased visibility of the hyperfluorescent BVN (right)

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BMC Ophthalmology

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