Associations between matrix metalloproteinase gene polymorphisms and glaucoma susceptibility: a meta-analysis

BMC Ophthalmology

Table 2 Characteristics of included studies on MMP-1 rs1799750 1G > 2G and MMP-2 rs243865C > T polymorphisms and glaucoma risk

First author	Year	Country	Racial/descent	Type	Genotyping	Case	Control	Genotype distribution						P for HWE	Source of controls
First author	Year	Country	Racial/descent	Type	Genotyping	Case	Control	Case			Control			P for HWE	Source of controls
rs1799750 1G > 2G								1G/1G	1G/2G	2G/2G	1G/1G	1G/2G	2G/2G
Tsironi	2009	Greece	Caucasian	XFG	PCR-RFLP	92	214	39	42	11	65	110	39	0.53	Hospital-based
Mossböck1	2010	Austria	Caucasian	POAG	PCR-RFLP	322	248	42	141	139	26	120	102	0.28	Hospital-based
Mossböck2	2010	Austria	Caucasian	XFG	PCR-RFLP	202	248	31	83	88	26	120	102	0.28	Hospital-based
Markiewicz	2013	Poland	Caucasian	POAG	PCR-RFLP	255	256	93	77	85	94	113	49	0.15	Hospital-based
Micheal1	2013	Pakistan	Asian	PACG	PCR-RFLP	82	118	25	36	21	53	45	20	0.06	Healthy-based
Micheal2	2013	Pakistan	Asian	POAG	PCR-RFLP	112	118	27	49	36	53	45	20	0.06	Healthy-based
rs243865C > T								C/C	C/T	T/T	C/C	C/T	T/T
Mossböck1	2010	Austria	Caucasian	POAG	PCR-RFLP	322	248	187	111	24	138	88	22	0.15	Hospital-based
Mossböck2	2010	Austria	Caucasian	XFG	PCR-RFLP	202	248	107	80	15	138	88	22	0.15	Hospital-based
Kaminska	2014	Poland	Caucasian	POAG	PCR-RFLP	268	311	159	89	20	175	123	13	0.13	Hospital-based

ISSN: 1471-2415