OR | 95% CI | P | I2 (%)a | OR | 95% CI | P | I2 (%)a | OR | 95% CI | P | I2 (%)a | OR | 95% CI | P | I2 (%)a | OR | 95% CI | P | I2 (%)a | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs17576 G > A | A vs. G | GA vs. GG | AA vs. GG | GA + AA vs. GG | AA vs. GG + GA | |||||||||||||||
Total | 1.10 | 0.80-1.51 | 0.56 | 85.1 | 0.80 | 0.67-0.97 | 0.02 | 0 | 1.07 | 1.07 0.52-2.19 | 0.86 | 85.5 | 0.87 | 0.60-1.24 | 0.44 | 73.7 | 1.23 | 0.69-2.18 | 0.48 | 85.5 |
Type | ||||||||||||||||||||
PACG | 1.01 | 0.62-1.62 | 0.98 | 90.6 | 0.83 | 0.68-1.03 | 0.09 | 16.3 | 1.10 | 0.43-2.86 | 0.84 | 88.0 | 0.88 | 0.56-1.37 | 0.57 | 78.9 | 1.25 | 0.56-2.85 | 0.58 | 87.7 |
POAG | 0.82 | 0.51-1.26 | 0.34 | 75.8 | 0.67 | 0.44-1.01 | 0.06 | 0 | 0.62 | 0.23-1.61 | 0.16 | 54.7 | 0.66 | 0.44-0.97 | 0.03 | 0 | 0.84 | 0.46-1.52 | 0.56 | 68.7 |
XFG | 0.95 | 0.72-1.25 | 0.71 | NA | 0.58 | 0.32-1.05 | 0.07 | NA | 0.90 | 0.50-1.62 | 0.29 | NA | 0.65 | 0.37-1.13 | 0.13 | NA | 1.10 | 0.76-1.61 | 0.60 | NA |
Ethnicity | ||||||||||||||||||||
Asian | 1.27 | 0.83-1.96 | 0.27 | 86.4 | 0.85 | 0.68-1.50 | 0.13 | 13.0 | 1.41 | 0.49-4.06 | 0.52 | 88.6 | 0.98 | 0.62-1.56 | 0.94 | 79.5 | 1.55 | 0.60-4.01 | 0.34 | 88.2 |
Caucasian | 0.80 | 0.50-1.22 | 0.30 | 77.5 | 0.67 | 0.45-1.00 | 0.05 | 0 | 0.61 | 0.33-1.12 | 0.11 | 52.0 | 0.66 | 0.45-0.97 | 0.03 | 0 | 0.81 | 0.43-1.53 | 0.52 | 81.0 |
Design | ||||||||||||||||||||
Heal-B | 1.08 | 0.88-1.33 | 0.46 | 0 | 0.79 | 0.52-1.18 | 0.25 | 50.1 | 1.00 | 0.26-3.81 | 1.00 | 84.7 | 0.78 | 0.44-1.37 | 0.38 | 76.5 | 1.14 | 0.39-3.37 | 0.81 | 79.0 |
Hosp-B | 1.83 | 0.51-6.54 | 0.35 | 96.0 | 0.77 | 0.50-1.17 | 0.22 | 20.7 | 2.22 | 0.28-17.62 | 0.45 | 94.6 | 1.40 | 0.37-5.35 | 0.62 | 90.3 | 2.51 | 0.46-13.57 | 0.27 | 94.7 |
Pop-B | 0.76 | 0.55-1.05 | 0.10 | 57.2 | 0.81 | 0.58-1.12 | 0.20 | 0 | 0.61 | 0.31-1.22 | 0.16 | 54.7 | 0.73 | 0.48-1.12 | 0.15 | 35.3 | 0.68 | 0.47-0.98 | 0.04 | 30.6 |
Genotyping | ||||||||||||||||||||
AB | 1.40 | 0.62-3.20 | 0.42 | 92.9 | 0.86 | 0.65-1.15 | 0.32 | 0 | 1.87 | 0.48-7.29 | 0.37 | 87.3 | 1.20 | 0.62-2.30 | 0.59 | 80.5 | 1.93 | 0.52-7.18 | 0.32 | 88.0 |
PCR-RFLP | 1.05 | 0.89-1.23 | 0.57 | 0 | 0.74 | 0.48-1.13 | 0.16 | 55.7 | 0.86 | 0.32-2.29 | 0.76 | 84.1 | 0.74 | 0.42-1.30 | 0.30 | 77.1 | 1.05 | 0.51-2.16 | 0.89 | 81.2 |
rs17577 G > A | A vs. G | GA vs. GG | AA vs. GG | GA + AA vs. GG | AA vs. GG + GA | |||||||||||||||
Total | 1.30 | 0.98-1.72 | 0.07 | 12.0 | 1.26 | 0.91-1.74 | 0.16 | 0 | 1.79 | 0.71-4.48 | 0.22 | 0 | 1.30 | 0.95-1.78 | 0.10 | 2.3 | 1.70 | 0.68-4.24 | 0.26 | 0 |
Ethnicity | ||||||||||||||||||||
Asian | 1.11 | 0.78-1.58 | 0.58 | 0 | 1.08 | 0.72-1.62 | 0.70 | 0 | 1.31 | 0.39-4.34 | 0.66 | 0 | 1.10 | 0.78-1.58 | 0.64 | 0 | 1.29 | 0.39-4.27 | 0.68 | 0 |
Design | ||||||||||||||||||||
Hosp-B | 1.11 | 0.78-1.58 | 0.58 | 0 | 1.08 | 0.72-1.62 | 0.70 | 0 | 1.31 | 0.39-4.34 | 0.66 | 0 | 1.10 | 0.78-1.58 | 0.64 | 0 | 1.29 | 0.39-4.27 | 0.68 | 0 |
rs3918249 C > T | T vs. C | CT vs. CC | TT vs. CC | CT + TT vs. CC | TT vs. CC + CT | |||||||||||||||
Total | 0.84 | 0.62-1.14 | 0.27 | 67.9 | 0.91 | 0.65-1.28 | 0.59 | 41.0 | 0.68 | 0.46-1.02 | 0.06 | 39.9 | 0.84 | 0.56-1.47 | 0.40 | 63.1 | 0.71 | 0.51-0.98 | 0.04 | 0 |
Ethnicity | ||||||||||||||||||||
Asian | 0.96 | 0.73-1.25 | 0.75 | 43.9 | 0.99 | 0.68-1.45 | 0.96 | 50.9 | 0.86 | 0.53-1.40 | 0.55 | 0 | 0.97 | 0.66-1.42 | 0.89 | 55.0 | 0.87 | 0.54-1.40 | 0.58 | 0 |
Design | ||||||||||||||||||||
Heal-B | 0.74 | 0.56-0.98 | 0.03 | 41.6 | 0.77 | 0.56-1.07 | 0.12 | 0 | 0.57 | 0.31-1.04 | 0.07 | 40.9 | 0.73 | 0.54-0.99 | 0.05 | 32.7 | 0.66 | 0.46-0.95 | 0.03 | 0 |
rs3918242 C > T | T vs. C | CT vs. CC | TT vs. CC | CT + TT vs. CC | TT vs. CC + CT | |||||||||||||||
Total | 1.13 | 0.60-2.13 | 0.70 | 82.5 | 1.37 | 0.82-2.28 | 0.23 | 61.7 | 0.62 | 0.11-3.33 | 0.58 | 70.5 | 1.27 | 0.68-2.36 | 0.46 | 78.5 | 0.57 | 0.12-2.68 | 0.48 | 65.4 |
Type | ||||||||||||||||||||
POAG | 1.20 | 0.69-2.06 | 0.52 | 73.0 | 1.51 | 1.09-2.08 | 0.01 | 31.8 | 0.72 | 0.16-3.23 | 0.67 | 56.2 | 1.36 | 0.81-2.28 | 0.24 | 59.7 | 0.65 | 0.16-2.64 | 0.55 | 50.1 |
Design | ||||||||||||||||||||
Heal-B | 0.81 | 0.57-1.13 | 0.22 | 0 | 1.02 | 0.98-1.54 | 0.91 | 0 | 0.25 | 0.07-0.92 | 0.04 | 0 | 0.92 | 0.60-1.34 | 0.60 | 0 | 0.25 | 0.07-0.89 | 0.03 | 0 |
rs3918254 C > T | T vs. C | CT vs. CC | TT vs. CC | CT + TT vs. CC | TT vs. CC + CT | |||||||||||||||
Total | 0.80 | 0.58-1.09 | 0.15 | 0 | 1.04 | 0.71-1.54 | 0.83 | 0 | NA | NA | NA | NA | 0.90 | 0.62-1.32 | 0.60 | 0 | NA | NA | NA | NA |
rs3787268 G > A | A vs. G | GA vs. GG | AA vs. GG | GA + AA vs. GG | AA vs. GG + GA | |||||||||||||||
Total | 1.06 | 0.78-1.43 | 0.72 | 40.3 | 1.13 | 0.83-1.54 | 0.44 | 0 | 1.08 | 0.32-3.62 | 0.90 | 72.7 | 1.11 | 0.83-1.50 | 0.49 | 0 | 1.02 | 0.30-3.51 | 0.97 | 75 |