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Table 2 Allele and genotype distribution of the rs11200638 polymorphism in studies included in the meta-analysis

From: Association between polymorphism rs11200638 in the HTRA1 gene and the response to anti-VEGF treatment of exudative AMD: a meta-analysis

 

Positive Responders

Frequency (A) (%)

Negative Responders

Frequency (A) (%)

Study (year)

Genotype

Genotype

 

N

GG

GA

AA

G/A

N

GG

GA

AA

G/A

McKibbin (2012) [36]

53

13

30

10

56/50

47.17%

51

14

25

12

53/49

48.04%

Orlin (2012) [37]

93

36

38

19

110/76

40.86%

56

21

24

11

64/46

41.07%

Abedi (2013) [38]

182

GG + AG = 148

34

NA

NA

28

GG + AG = 15

13

NA

NA

Hagstrom (2013) [39]

251

81

123

47

285/217

43.23%

583

193

275

115

661/505

43.31%

Park (2014) [40]

136

19

54

63

92/180

66.18%

137

17

52

68

86/188

68.61%

  1. NA not avaliable