Fig. 6

Sensation of coolness and changes in ocular parameters after a single application of vehicle or C3, 2 mg/mL. (a) Visual analogue scale (VAS) for coolness on ocular surface. (b) Dry eye symptom score. (c) Tear break-up time (TBUT) in sec. (d) Basal tear secretion in mm. (e) Keratoepitheliopathy score. * P < 0.05, **P < 0.01, compared to baseline value and vehicle (n = 30 in each group)