Fig. 1
From: Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia
Effect of CoCl2 treatment on the SRA01/04 cells. a-f Transmission images of SRA01/04 cultured in the presence (a, b, c) and absence (d, e, f) of 150 μM CoCL2for 12 h (a, d), 24 h (b, e) and 48 h (c, f). The morphology of the SRA01/04cells at 48 h after CoCL2treatment (c) appeared no cell polarity and lost cell junction. g-i western blot images (g) and average relative band intensity of Keratin (h) and Fibronectin (i) in SRA01/04 cells cultured with 150 μM CoCL2 for 12 h (group1), 24 h (group2), 48 h (group3). At 48 h of CoCL2 stimulation, the expression of Keratin decreased most significantly (P < 0.05), and Fibronectin increased most significantly (P < 0.05)