Table 1 Main outcome measures at baseline and different follow-ups (mean ± SD)

0.44 ± 0.22

0.69 ± 0.19

0.73 ± 0.18

0.70 ± 0.18

11.535

<0.001

404.84 ± 28.34

261.38 ± 26.69

227.38 ± 25.57

233.53 ± 23.69

27.227

<0.001

−3.39 ± 0.89

−1.96 ± 0.29

−1.94 ± 0.29

−2.45 ± 0.13

4.744

0.004

29.76 ± 1.51

31.74 ± 1.56

31.51 ± 1.38

31.19 ± 1.61

7.108

<0.001

28.96 ± 1.78

32.41 ± 1.66

32.46 ± 1.50

31.90 ± 1.84

17.830

<0.001

1.97 ± 0.24

1.47 ± 0.27

1.34 ± 0.24

1.53 ± 0.24

6.329

0.001