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Fig. 5 | BMC Ophthalmology

Fig. 5

From: MiRNAs regulate oxidative stress related genes via binding to the 3′ UTR and TATA-box regions: a new hypothesis for cataract pathogenesis

Fig. 5

Predicted binding between cataract-regulated miRNAs and the TATA-box region/3′ UTR of oxidative stress related genes. Online resource miRWalk [17, 18] and RNAhybrid [19] was used to predict binding between miR-204-5p/miR-378a-3p and the 3′ UTR of target mRNA TXNIP/SOD1 (a and b, upper part). The Eukaryotic Promoter Database [15, 16] and RNAhybrid [19] were used to predict binding between miR-204-5p/miR-378a-3p and the TATA-box region of target mRNA ALDH1A3/TXNIP promoters (a and b, lower part). mfe: minimum free energy

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BMC Ophthalmology

ISSN: 1471-2415

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