Skip to main content

Table 1 Regulated miRNAs in Cataractous Samples and Target mRNA Gene Symbols

From: MiRNAs regulate oxidative stress related genes via binding to the 3′ UTR and TATA-box regions: a new hypothesis for cataract pathogenesis

miRNA names

regulation

Average fold changea

3′ UTR target

TATA-box target

has-miR-1207-5p

down

0.22

CYCS

FTL, MT1E, MT1G, MT1H, MT1M

has-miR-124-3p

down

0.36

CYB5A, CYP1B1

TXN

has-miR-204-3p

down

0.43

CYP1B1

None

has-miR-204-5p

down

0.43

TXNIP

ALDH1A3, TF

has-miR-222-3p

up

2.60

PRDX4, TXN

CYP1A2, CYP1B1

has-miR-378a-3p

up

2.80

SOD1

TXNIP

  1. aAverage fold change values were means of 3 separate array results (fold change = cataractous lens sample/transparent lens sample)