Fig. 2

a Color and b Fundus Autofluorescence (FAF) images of the left eye of a 36 yr. female patient (RD1–12) presenting consistency with a cone-rod dystrophy rather than the reported retinitis pigmentosa that has been described with the C2orf71 gene in the literature. c Montage (3-field) color funduscopic image of the left eye of a 55 yr. female patient (RD11–05) with retinitis pigmentosa showing diffuse bony spicules (*1), vascular attenuation (*2), and optic nerve pallor (*3). d Color and e FAF images of the right eye of a 48 yr. female patient (RD14–05) with advanced rod-cone dystrophy showing macular atrophic changes, severely attenuated vessels (*2), mottling of the retinal pigment epithelium and bony spicules (*1), as well as optic nerve head waxy pallor (*4). f Right eye funduscopic appearance of a 74 yr. female patient (RD11–06) with advanced retinal degeneration