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Table 7 Correlation between duration of diabetes and altered aqueous cytokines/ chemokines/growth factors in patients with type 2 diabetes

From: Assessment of biomarkers using multiplex assays in aqueous humor of patients with diabetic retinopathy

 

Cytokines/chemokines/growth factors

Correlation coefficients

P

Duration

IL-6

0.350

<0.001*

IL-8

0.563

<0.001*

IP-10

0.444

<0.001*

LIF

0.578

<0.001*

HGF

0.435

<0.001*

VEGF-A

0.324

<0.001*

IL-1α

−0.341

<0.001*

IL-4

−0.383

<0.001*

IL-9

−0.364

<0.001*

IL-21

−0.342

<0.001*

IL-23

−0.324

<0.001*

IL-27

−0.329

<0.001*

IL-31

−0.434

<0.001*

TNF-β

−0.318

<0.001*

IFN-α

−0.203

0.013*

GROα

−0.448

<0.001*

RANTES

−0.296

<0.001*

  1. IL interleukin, IP interferon inducibleprotein, LIF leukaemia inhibitor factor, HGF hepatocyte growth factor, VEGF vascular endothelial growth factor, TNF tumour necrosis factor, IFNγ interferon-γ, GRO growth regulated oncogene, RANTES regulated upon activation, normal T cell expressed and presumably secreted
  2. Data are expressed as the mean ± SD (pg/ml)
  3. * p < 0.05