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Table 8 Correlation between HbA1c and altered aqueous cytokines/chemokines/growth factors in patients with type 2 diabetes

From: Assessment of biomarkers using multiplex assays in aqueous humor of patients with diabetic retinopathy

 

Cytokines/chemokines/growth factors

Correlation coefficients

P

HbA1c (%)

IL-6

0.347

<0.001*

IL-8

0.546

<0.001*

IP-10

0.430

<0.001*

LIF

0.567

<0.001*

HGF

0.421

<0.001*

VEGF-A

0.319

<0.001*

IL-1α

−0.341

<0.001*

IL-4

−0.367

<0.001*

IL-9

−0.362

<0.001*

IL-21

−0.339

<0.001*

IL-23

−0.328

<0.001*

IL-27

−0.333

<0.001*

IL-31

−0.432

<0.001*

TNF-β

−0.311

<0.001*

IFN-α

−0.201

<0.001*

GROα

−0.443

<0.001*

RANTES

−0.310

<0.001*

  1. IL interleukin, IP interferon inducibleprotein, LIF leukaemia inhibitor factor, HGF hepatocyte growth factor, VEGF vascular endothelial growth factor, TNF tumour necrosis factor, IFNγ interferon-γ, GRO growth regulated oncogene, RANTES regulated upon activation, normal T cell expressed and presumably secreted
  2. Data are expressed as the mean ± SD (pg/ml)
  3. * p < 0.05