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Table 2 Roc curve analysis for the ability of different parameters to differentiate between forme fruste keratoconus eye and control eyes

From: Objective and subjective diagnostic parameters in the fellow eye of unilateral keratoconus

parameter

AUC

SE

95%CI

P value

cutoff

sensitivity

specificity

Ks

0.6

0.092

0.42,0.78

0.353

42.5

64%

50%

Kf

0.5

0.091

0.3,0.6

0.93

NA

NA

NA

Km

0.82

0.06

0.68,0.95

0.353

42.4

64%

80%

CCT

0.58

0.1

0.38,0.77

0.446

NA

NA

NA

CT min

0.61

0.6

0.4,0.8

0.3

516

60%

80%

PE

0.45

0.129

0.02,0.07

0.67

NA

NA

NA

BDE

0.60

0.094

0.41,0.77

0.38

3.5

53%

80%

PPI avg

0.404

0.016

o.19,o.61

0.37

NA

NA

NA

PPI max

0.64

0.093

0.64,0.83

0.174

1.31

50%

70%

ART avg

0.57

0.10

0.36,0.78

0.486

NA

NA

NA

ART min

0.56

0.10

0.35,0.77

0.551

NA

NA

NA

ART max

0.88

0.056

0.77,0.99

< 0.001

404

82%

70%

D index

0.67

0.102

0.47,0.87

0.097

1.2

71%

60%

  1. ART Ambrosio relational thickness, AUC area under curve, avg. average, BDE back difference elevation, CCT central corneal thickness, CI confidence interval, CT min minimum corneal thickness, D index multimetric D, Kf flat keratometry, Km mean keratometry, Ks steep keratometry, max maximum, min minimum, NA not applicable,SE standard error, PE posterior elevation, PPI pachymetric progression index