Fig. 3
From: The antioxidant effects of riluzole on the APRE-19 cell model injury-induced by t-BHP
Activation of two-pore domain potassium channels (K2P) prevents cytochrome c (Cyt-c) release to the cytoplasm in culture human retinal pigment epithelia (ARPE-19) cells. a The release of mitochondrial Cyt-c was estimated by examining the Cyt-c protein content in mitochondria and the extracted mitochondria-free cytosolic fraction by Western blot. COXIV and β-actin were used as loading controls. b Quantitative analysis of the percentage of Cyt-c in mitochondria and cytoplasm of ARPE-19 cells