Link between neurodegeneration and trabecular meshwork injury in glaucomatous patients

BMC Ophthalmology

Table 4 Correlations among cytokines in POAG

ρ/P value	BDNF	Cat D	sICAM-1	MPO	sNCAM	sVCAM-1	PAI-1
BDNF	–	−0.103	−0.402	−0.192	−0.378	−0.412	−0.455
Cathepsin D	0.631	–	0.432	0.072	0.369	0.592	0.290
sICAM-1	0.052	0.035	–	0.425	0.743	0.737	0.751
MPO	0.368	0.740	0.038	–	0.312	0.269	0.551
sNCAM	0.069	0.076	0.000*	0.138	–	0.603	0.775
sVCAM-1	0.046	0.002*	0.000*	0.204	0.002*	–	0.620
PAI-1	0.025	0.169	0.000*	0.005*	0.000*	0.001*	–

POAG, primary open angle glaucoma; BDNF, brain-derived neurotrophic factor; Cat D,cathepsin D; sICAM, soluble intercellular adhesion molecule; MPO, myeloperoxidase; sNCAM, soluble neural cell adhesion molecule; sVCAM, soluble vascular cell adhesion molecule; PAI, plasminogen activator inhibitor
Correlation coefficient (ρ) and P values for each pair of cytokines are calculated by the Spearman’s correlation test
The P values are shown on the lower left side and ρ on the upper right side of the table
*Significance level at 5% (P < 0.0083), by Bonferroni correction for multiple comparisons

ISSN: 1471-2415