Table 11 Comparison of tear cytokine levels at baseline between dry eye disease and control populations (all enrolled population)
Variable pg/mL/mm | All cases (n = 217) | All controls (n = 67) | P-value | |
|---|---|---|---|---|
EGF | N | 164 | 51 | |
Mean (SD) | 2074.88 (3739.842) | 1724.86 (2632.770) | 0.5348 | |
Min-Max | 0.0–21,938 | 0.0–12,827 | ||
IFN-γ | N | 164 | 51 | |
Mean (SD) | 23.16 (125.014) | 18.77 (57.550) | 0.8083 | |
Min-Max | 0.0–1168.4 | 0.0–322.5 | ||
IL-1α | N | 164 | 51 | |
Mean (SD) | 214.58 (404.996) | 159.45 (223.319) | 0.3543 | |
Min-Max | 0.0–3244.0 | 0.0–1241.3 | ||
IL-1β | N | 164 | 51 | |
Mean (SD) | 55.89 (155.754) | 25.02 (36.211) | 0.1626 | |
Min-Max | 0.0–1580.9 | 0.0–194.6 | ||
IL-2 | N | 164 | 51 | |
Mean (SD) | 7.79 (25.646) | 4.07 (7.751) | 0.3091 | |
Min-Max | 0.0–253.4 | 0.0–33.3 | ||
IL-4 | N | 164 | 51 | |
Mean (SD) | 124.53 (433.605) | 152.13 (331.354) | 0.6765 | |
Min-Max | 0.0–3229.7 | 0.0–1913.5 | ||
IL-6 | N | 164 | 51 | |
Mean (SD) | 147.45 (476.145) | 104.72 (290.994) | 0.5451 | |
Min-Max | 0.0–3996.7 | 0.0–1801.2 | ||
IL-8 | N | 164 | 51 | |
Mean (SD) | 722.86 (1617.582) | 563.38 (769.371) | 0.4974 | |
Min-Max | 0.0–15,528 | 0.0–3240.8 | ||
IL-10 | N | 164 | 51 | |
Mean (SD) | 29.06 (112.567) | 34.11 (104.294) | 0.7765 | |
Min-Max | 0.0–1175.0 | 0.0–727.5 | ||
IL-13 | N | 164 | 51 | |
Mean (SD) | 48.48 (181.660) | 19.36 (44.051) | 0.2586 | |
Min-Max | 0.0–1662.7 | 0.0–277.6 | ||
IL-17 | N | 164 | 51 | |
Mean (SD) | 15.77 (91.369) | 16.17 (67.701) | 0.9768 | |
Min-Max | 0.0–911.4 | 0.0–394.7 | ||
IP-10 | N | 164 | 51 | |
Mean (SD) | 42,229.7 (61,361.73) | 33,137.9 (37,534.33) | 0.3182 | |
Min-Max | 0.0–449,861 | 0.0–144,295 | ||
TNF-α | N | 164 | 51 | |
Mean (SD) | 13.30 (66.885) | 5.95 (17.235) | 0.4387 | |
Min-Max | 0.0–642.1 | 0.0–86.1 |