Structural changes of the macula and optic nerve head in the remaining eyes after enucleation for retinoblastoma: an optical coherence tomography study

Table 1 Comparison between the control group and study groups as regards demographic data using independent sample t-test

Parameter	Control group	Study group (I)	Study group (II)	P-value [control group versus study group (I)]	P-value [control group versus study group (II)]	P-value [study group (I) versus study group (II)]
Parameter	Mean ± SD			P-value [control group versus study group (I)]	P-value [control group versus study group (II)]	P-value [study group (I) versus study group (II)]
Mean age (years)	12.77 ± 4.16	10.73 ± 4.0	11.53 ± 3.49	0.12	0.30	0.56
Mean age at presentation (months)	N/A	23.13 ± 13.36	15.20 ± 7.76	N/A	N/A	0.06
Sex distribution No. (%)
Male	24 (80.0)	8 (53.3)	9 (60.0)	0.06	0.15	0.71^a
Female	6 (20.0)	7 (46.7)	6 (40.0)
Diagnosis of retinoblastoma No. (%)
Right	N/A	7 (46.7)	10 (66.7)	N/A	N/A	0.27^a
Left		8 (53.3)	5 (33.3)
Family history No. (%)
Negative	N/A	15 (100.0)	14 (93.3)	N/A	N/A	1.0^a
Positive		0 (0.0)	1 (6.7)
Consanguinity No. (%)
Negative	N/A	13 (86.7)	15 (100.0)	N/A	N/A	0.48^a
Positive		2 (13.3)	0 (0.0)
Mean duration of follow up (years)	N/A	7.93 ± 3.49	10.38 ± 3.73	N/A	N/A	0.07
Mean BCVA (Log.MAR)	0.11 ± 0.03	0.11 ± 0.05	0.11 ± 0.02	0.64	1.00	0.66
Mean spherical Equivalent (diopters)	0.83 ± 0.72	1.28 ± 0.82	1.12 ± 0.60	0.08	0.16	0.53
Mean IOP (mmHg)	11.6 ± 1.69	11.9 ± 1.87	11.53 ± 1.64	0.56	0.90	0.54
Average of mean deviation (decibels)	−1.37 ± 1.43	−1.62 ± 1.29	−1.41 ± 1.80	0.56	0.93	0.72
Mean of pattern standard deviation (decibels)	1.14 ± 1.05	1.12 ± 1.04	1.14 ± 1.07	0.95	0.99	0.95

N/A, not applicable; SD, standard deviation; No., number; Log.MAR, logarithm of minimum angle of resolution
^aComparison by Chi-square test

ISSN: 1471-2415