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Table 2 Comparison between the control group and study groups as regards total and inner retinal layers thicknesses at the macula using independent sample t-test

From: Structural changes of the macula and optic nerve head in the remaining eyes after enucleation for retinoblastoma: an optical coherence tomography study

Parameter

Control group

Study group (I)

Study group (II)

P-value [control group versus study group (I)]

P-value [control group versus study group (II)]

P-value [study group (I) versus study group (II)]

Mean (μm) ± SD

A. Central foveal thickness (Central 1 mm)

268.09 ± 23.49

246.8 ± 15.33

249.85 ± 17.69

0.001

0.04

0.71

B. Total macular thickness

3 mm ring

    

Superior

350.93 ± 21.87

343.08 ± 12.02

331.42 ± 10.17

0.08

0.002

0.04

Nasal

345.13 ± 17.77

342.14 ± 9.29

330.85 ± 10.15

0.12

0.01

0.03

Temporal

330.64 ± 15.26

332.35 ± 12.52

318.28 ± 8.38

0.60

0.009

0.01

Inferior

336.87 ± 21.34

338.83 ± 12.76

330.42 ± 12.25

0.71

0.3

0.18

6 mm ring

Superior

307.29 ± 15.82

310.00 ± 1.15

293.42 ± 8.24

0.43

0.004

0.001

Nasal

322.93 ± 16.64

322.58 ± 12.6

310.14 ± 10.94

0.94

0.026

0.04

Temporal

291.06 ± 14.18

297.42 ± 10.23

280.28 ± 11.44

0.11

0.05

0.007

Inferior

300.64 ± 19.12

303.91 ± 14.93

292.85 ± 13.51

0.56

0.23

0.12

C. Mac RNFL thickness

    

Average Mac RNFL

27.35 ± 5.02

28.19 ± 4.85

23.55 ± 4.72

0.62

0.08

0.06

3 mm ring

Superior

27.93 ± 7.19

26.5 ± 12.0a

22.14 ± 6.01

0.90b

0.05

0.08b

Nasal

20.16 ± 7.96

19.68 ± 7.35

17.14 ± 5.63

0.92

0.26

0.35

Temporal

12.77 ± 8.61

43.83 ± 7.98

9.42 ± 7.29

0.46

0.31

0.16

Inferior

24.64 ± 6.23

24.08 ± 7.31

20.85 ± 4.48

0.81

0.08

0.25

6 mm ring

Superior

35.48 ± 3.62

37.83 ± 6.60

33.0 ± 5.53

0.26

0.29

0.11

Nasal

45.13 ± 6.72

43.0 ± 2.75a

40.57 ± 6.37

0.33b

0.12

0.15b

Temporal

15.96 ± 6.27

18.08 ± 6.25

12.71 ± 4.99

0.33

0.16

0.06

Inferior

36.74 ± 4.39

36.75 ± 7.27

32.57 ± 4.99

0.99

0.07

0.16

D. Ganglion cell layer (GCL) thickness

Average GCL thickness

80.76 ± 6.93

80.04 ± 4.59

74.45 ± 4.49

0.69

0.01

0.02

3 mm ring

Superior

93.32 ± 9.35

91.0 ± 6.03

86.85 ± 5.78

0.16

0.03

0.16

Nasal

97.45 ± 8.67

93.91 ± 6.69

89.14 ± 6.59

0.17

0.02

0.15

Temporal

92.64 ± 13.17

90.58 ± 6.34

80.57 ± 9.50

0.49

0.01

0.03

Inferior

92.87 ± 11.64

90.57 ± 8.34

86.28 ± 8.63

0.48

0.12

0.31

6 mm ring

Superior

61.25 ± 6.32

62.41 ± 6.45

60.0 ± 3.0a

0.60

0.51b

0.33b

Nasal

70.54 ± 6.45

71.33 ± 4.88

64.28 ± 6.89

0.67

0.06

0.04

Temporal

72.64 ± 8.68

74.08 ± 7.85

70.43 ± 4.57

0.61

0.35

0.21

Inferior

65.35 ± 8.72

66.41 ± 6.67

59.28 ± 8.86

0.67

0.13

0.09

E. Ganglion cell complex (GCC) thickness

Average GCC thickness

108.10 ± 7.39

108.62 ± 2.64

98.0 ± 6.42

0.87

0.004

0.004

3 mm ring

      

Superior

121.19 ± 10.37

119.5 ± 8.5a

109.0 ± 9.42

0.68b

0.01

0.01b

Nasal

117.54 ± 8.64

113.83 ± 5.81

106.28 ± 5.15

0.11

0.0004

0.01

Temporal

105.32 ± 9.66

105.58 ± 3.98

90.0 ± 8.98

0.91

0.003

0.003

Inferior

117.61 ± 11.9

116.0 ± 4.31

107.14 ± 9.97

0.39

0.04

0.07

6 mm ring

      

Superior

96.64 ± 7.96

100.25 ± 6.67

91.71 ± 4.95

0.14

0.05

0.006

Nasal

115.74 ± 9.50

114.91 ± 5.64

104.85 ± 9.65

0.73

0.02

0.034

Temporal

88.61 ± 8.38

92.17 ± 5.50

83.14 ± 3.08

0.11

0.008

< 0.001

Inferior

102.16 ± 10.71

103.17 ± 7.12

91.86 ± 13.25

0.72

0.09

0.07

  1. SD, standard deviation; μm, micron
  2. aMedian ± Interquartile range;bComparison by Mann Whitney U test