Elevated inflammatory cytokines in aqueous cytokine profile in HIV-1 infected patients with cataracts in Uganda

BMC Ophthalmology

Table 2 The proportion of patients with detectable cytokines in the aqueous of patients that had cataract surgery at RHSP, south-western Uganda

Cytokine	HIV+		HIV-		p-value
Cytokine	Number	Percentage	Number	Percentage	p-value
IL-6	25	(100%)	25	(100%)	–
IFN-g	17	(68%)	8	(32%)	0.037*
GM-CSF	19	(86%)	22	(92%)	0.659
TNF-a	21	(95%)	12	(50%)	0.001*
IL-2	15	(68%)	5	(21%)	0.003*
IL-4	17	(77%)	8	(33%)	0.004*
IL-8	25	(100%)	25	(100%)	–
IL-10	24	(96%)	17	(68%)	0.023*

*Significant difference in proportion of cases with detectable cytokines higher among HIV positive cases compared to HIV negative cases
IL-6 Interleukin 6, IFN-g Interferon –gamma, GM-CSF Granulocyte macrophage colony stimulating factor, TNF-a Tumour necrosis factor alpha, IL-2 Interleukin 2, IL-4 Interleukin 4, IL-8 Interleukin 8, IL-10 Interleukin 10, RHSP Rakai Health Service Programme

ISSN: 1471-2415