Elevated inflammatory cytokines in aqueous cytokine profile in HIV-1 infected patients with cataracts in Uganda

BMC Ophthalmology

Table 5 Cytokine levels in categorized CD4 count levels among HIV infected individuals that had cataract surgery at RHSP, south-western Uganda

	CD4 < 200cells/mm3		CD4 ≥ 200cells/mm3		P-value at α = 0.05*	P-value at α = 0.00625^§
	Median (IQR)		Median (IQR)		P-value at α = 0.05*	P-value at α = 0.00625^§
IL-6	1603	[374, 3677]	1190	[625, 12,463]	0.446	0.446
IFN-g	753	[154, 1290]	1469	[304, 2898]	0.539	0.539
GM-CSF	1872	[1753, 1994]	1632	[1307, 1872]	0.107	0.107
TNF-a	79	[6, 146]	230	[95, 530]	0.022*	0.022
IL-2	66	[25, 129]	147	[46, 271]	0.343	0.343
IL-4	10	[10, 34]	90	[9, 110]	0.032*	0.032
IL-8	448	[368, 1364]	836	[447, 3439]	0.319	0.319
IL-10	232	[209, 278]	365	[250, 535]	0.109	0.109

*Significant at α = 0.05
^§Significant at α = 0.00625 corrected with Bonferroni correction for multiple comparisons
IL-6 Interleukin 6, IFN-g Interferon –gamma, GM-CSF Granulocyte macrophage colony stimulating factor, TNF-a Tumour necrosis factor alpha, IL-2 Interleukin 2, IL-4 Interleukin 4, IL-8 Interleukin 8, IL-10 Interleukin 10, IQR Interquartile range, RHSP Rakai Health Service Programme

ISSN: 1471-2415