Comparison of efficacy between anti-vascular endothelial growth factor (VEGF) and laser treatment in Type-1 and threshold retinopathy of prematurity (ROP)

Table 2 Quality assessment of randomized controlled trials

Domain	Review authors’ judgement	Option	Mintz-Hittner 2011 [13]	Moran 2014 [12]	Lepore 2014 [24]	Karkhaneh 2016 [25]
Sequence generation	Was the allocation sequence adequately generated?	Yes/Unclear/No	YES	Unclear	YES	Unclear
Allocation concealment	Was allocation adequately concealed?	Yes/Unclear/No	NO	NO	NO	NO
Blinding of participants and personnel	Was knowledge of the allocated intervention adequately prevented during the study?	Yes/Unclear/No	NO	NO	Unclear	NO
Blinding of outcome assessors	Was knowledge of the allocated intervention adequately prevented during the study?	Yes/Unclear/No	NO	NO	NO	NO
Incomplete outcome data	Were incomplete outcome data adequately addressed?	Yes/Unclear/No	YES	YES	YES	YES
Selective outcome reporting	Are reports of the study free of suggestion of selective outcome reporting?	Yes/Unclear/No	YES	YES	YES	YES
Other sources of bias	Was the study apparently free of other problems that could put it at a high risk of bias?	Yes/Unclear/No	YES	YES	YES	YES

ISSN: 1471-2415