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Fig. 2 | BMC Ophthalmology

Fig. 2

From: Antimicrobial efficacy of corneal cross-linking in vitro and in vivo for Fusarium solani: a potential new treatment for fungal keratitis

Fig. 2

Eyes from each group after infection. a All mice were photographed every 24 h for seven successive days(× 16). b Efficacy of each treatment was evaluated under the Schreiber scoring system. There were severe corneal infiltrates, clouding and anterior chamber hypopyon in the group A. Statistically, there were big differences between Group B and Group C compared to Group A. Mean ± SD, n = 10, *p < 0.05 Vs Cont, **p < 0.01 Vs Cont, Group A: no treatment (control); Group B: CXL treatment for two minutes; Group C: CXL treatment for three minutes. c The CFUs was obtained in culture from each group, in 1 day, 3, 7,10 days after modeling. There was a statistically significant decrease in CFUs in both group B and group C compared to group A. n = 10, *p < 0.05 Vs Cont, **p < 0.01 Vs Cont, Group A: no treatment (control); Group B: CXL treatment for two minutes; Group C: CXL treatment for three minutes. d Scatter plots of correlation between corneal lesions and the fungal colonies in each group of mice. Mean ± SD, n = 10, *p < 0.05 Vs Cont, **p < 0.01 Vs Cont, Group A, control group; Group B, treated with CXL for 2 min; Group C, treated with CXL for 3 min

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