Predictive multi-imaging biomarkers relevant for visual acuity in idiopathic macular telangiectasis type 1

BMC Ophthalmology

Table 2 Associations of baseline spectral-domain optical coherence tomography and optical coherence tomography angiography parameters with baseline logMAR visual acuity

Parameters	MT type 1 eyes	r	p value
FAZ of SCP (mm²)	0.45 ± 0.15	0.451	0.106
FAZ of DCP (mm²)	0.78 ± 0.35	0.521	0.056
Microvascular density of SCP (%)	46.47 ± 3.42	−0.652	0.012
Microvascular density of DCP (%)	47.25 ± 4.69	− 0.700	0.005
CMT (μm)	385.19 ± 75.21	0.682	0.007
Total area of macular oedema (mm²)	0.08 ± 0.10	0.443	0.112
Largest area of macular edema (mm²)	0.08 ± 0.09	0.512	0.061
Length of EZ disruption (μm)	642.26 ± 349.66	0.681	0.007
Area of EZ disruption (mm²)	0.93 ± 1.22	0.27	0.351
Total area of EZ disruption (mm²)	3.22 ± 2.02	0.649	0.012
Length of ELM disruption (μm)	372.57 ± 279.16	0.699	0.005
Length of DRIL disruption (μm)	480.79 ± 340.73	0.707	0.005

p-values indicate the relationships between logMAR VA and spectral domain OCT and OCTA parameters
OCT spectral domain optical coherence tomography, OCTA optical coherence tomography angiography, logMAR logarithm of the minimal angle of resolution, VA visual acuity, MT idiopathic macular telangiectasia, FAZ foveal avascular zone, SCP superficial capillary plexus, DCP deep capillary plexus, CMT central macular thickness, EZ ellipsoid zone, ELM external limiting membrane, DRIL disorganization of retinal inner layers, r Pearson’s correlation coefficient

ISSN: 1471-2415