Fig. 1

EZ band measurement: EZ limit was considered where the hyperreflective band decline to zero. In a, b and e, f horizontal scan passing through the fovea of two couples of siblings affected by RP acquired in 2010, in c, d and g, h same scan of same patients acquired 6 years later (2016). Patient in a was 17 years old and in 2010 and 23 years old in 2016 (c). His brother (b) was 18 years old in 2010 and 24 years old in 2016 (d). Patient in e was 14 years old and in 2010 and 20 years old in 2016 (g). His brother (f) was 20 years old in 2010 and 26 years old in 2016 (h)