Fig. 3

Forest plot of the random effects via BULP (Best Unbiased Linear Predictions) derived from the fitted model of the progression rate. BULP are the best prediction of the group mean (Family or subject), given the observations, from mixed models. The estimated intercept is indicated filled dot and numeric values are reported above each dot. Horizontal lines represent the 95% confidence intervals of the estimates. Reported estimates refer to the intercepts on the log-link function scale of the model and are ordered based on the estimated intercept of the family. Notice how subjects belonging to the same family show very variable estimated intercepts