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Fig. 1 | BMC Ophthalmology

Fig. 1

From: Intermittent high glucose-induced oxidative stress modulates retinal pigmented epithelial cell autophagy and promotes cell survival via increased HMGB1

Fig. 1

Intermittent high glucose induces significant oxidative stress and inhibits proliferative activity in ARPE-19 cells. a: Proliferative activity was decreased in both constant high glucose-treated cells and Intermittent glucose induced a more remarkable decrease in proliferative activity when compared to constant high glucose. b-c: Intermittent high glucose resulted in dramatic significantly higher fluorescence of cellular ROS marker DCFDA than constant high glucose and normal glucose. d: MDA concentrations of intermittent high glucose-treated cells was higher than that of constant high glucose and normal glucose. e: SOD concentrations in intermittent high glucose-treated cells was lower than that in constant high glucose and normal glucose. (*p < 0.05 vs. control, #p < 0.05 vs. HG)

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