Comparison of clinical characteristics and antibiotic susceptibility between Pseudomonas aeruginosa and P. putida keratitis at a tertiary referral center: a retrospective study

Table 4 Risk factors for poor clinical outcome* in Pseudomonas keratitis^† (univariate and multivariate logistic regression analysis^‡)

Variables	Univariate analysis			Multivariate analysis
Variables	OR	95% CI	p-value	OR	95% CI	p-value
Hypopyon	3.57	0.98–12.97	0.053	9.02	1.33–61.25	0.024
Epithelial healing time ≥ 10 (days)	4.91	1.17–20.62	0.030	–	–	–
Age ≥ 50 (years)	5.57	1.33–23.44	0.019	4.85	0.74–31.68	0.099
Nonuse of CLs	7.86	0.91–67.57	0.060	–	–	–
Previous ocular surgery	9.00	1.56–51.95	0.014	6.48	0.72–58.65	0.097
Previous OSD	16.11	3.38–76.76	< 0.001	10.79	1.67–69.76	0.012

CI confidence interval, CL contact lens, OSD ocular surface disease, OR odds ratio
*The clinical outcomes were assessed at the end of three months or at the completion of treatment and classified into three groups, as defined by Green [11].
†Total cohort of P. aeruginosa and P. putida keratitis, total n = 48: One young child in the P. aeruginosa group who could not read letters was excluded
‡Multivariate logistic regression analysis was performed using the backward-conditional method for the factors with a p-value < 0.1 in univariate logistic regression analysis

ISSN: 1471-2415