Fig. 4
From: Microglia enhanced the angiogenesis, migration and proliferation of co-cultured RMECs
Effects of static or activated microglia on angiogenesis relative factors expression of RMECs. a VEGF-A. b PDGF-BB. Compared with control RMECs, microglia significantly increased expression and release of VEGF-A and PDGF-BB in RMECs. LPS activated microglia enhanced the effects of static microglia to RMECs. Each bar graph indicates means ± SD of three independent experiments. *Significant difference in results between the two compared groups. *P < 0.05 using one-way ANOVA. **P < 0.01 using one-way ANOVA. Abbreviations: Con, control RMECs (i.e., cultured without microglia); MG, REMCs co-cultured with static microglia; LPS-MG, REMCs co-cultured with activated microglia; LPS, lipopolysaccharide; VEGF-A, Vascular endothelial growth factor-A; PDGF-BB, Platelet-derived growth factor-BB. (Page 11, paragraph 2)