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Fig. 5 | BMC Ophthalmology

Fig. 5

From: Microglia enhanced the angiogenesis, migration and proliferation of co-cultured RMECs

Fig. 5

Effects of static or activated microglia on tube formation of RMECs. a-c One representative experiment of tube formation of three different groups at 4 h. d-g Total tube length, number of nodes, number of branches, total branching length quantified by ImageJ. Both static and LPS-activated microglia stimulated tube formation in the RMECs. In addition, the effects on RMEC tube formation were enhanced by the activated microglia compared with the static microglia. Each bar graph indicates means ± SD of three independent experiments. Significant difference in results between the two compared groups. *P < 0.05 using one-way ANOVA. **P < 0.01 using one-way ANOVA. Abbreviations: Con, control RMECs (i.e., cultured without microglia); MG, REMCs co-cultured with static microglia; LPS-MG, REMCs co-cultured with activated microglia; LPS, lipopolysaccharide. (Page 11, paragraph 3)

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