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Table 2 The percentage of patients who showed changes in dry eye symptoms and ocular signs after 4 weeks of topical 3% diquafosol ophthalmic solution administration

From: Therapeutic effects of 3% diquafosol ophthalmic solution in patients with short tear film break-up time-type dry eye disease

Changes after treatment

No. patients (%)

Improved

No change

Worsened

Subjective dry eye symptom

55 (78.6)

15 (21.4)

0 (0)

Tear film break-up timea

46 (65.7)

22 (31.4)

2 (2.9)

Ocular staining score

44 (62.8)

23 (32.9)

3 (4.3)

  1. aAn increase in tear film break-up time after treatment was defined as “Improved, and a decrease as “Worsened”. The same values of tear film break-up time before and after treatment were defined as “No change”