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Table 2 The percentage of patients who showed changes in dry eye symptoms and ocular signs after 4 weeks of topical 3% diquafosol ophthalmic solution administration

From: Therapeutic effects of 3% diquafosol ophthalmic solution in patients with short tear film break-up time-type dry eye disease

Changes after treatment No. patients (%)
Improved No change Worsened
Subjective dry eye symptom 55 (78.6) 15 (21.4) 0 (0)
Tear film break-up timea 46 (65.7) 22 (31.4) 2 (2.9)
Ocular staining score 44 (62.8) 23 (32.9) 3 (4.3)
  1. aAn increase in tear film break-up time after treatment was defined as “Improved, and a decrease as “Worsened”. The same values of tear film break-up time before and after treatment were defined as “No change”