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Table 3 The age of patients who showed improvement in dry eye symptoms and ocular signs after 4 weeks of topical 3% diquafosol ophthalmic solution administration

From: Therapeutic effects of 3% diquafosol ophthalmic solution in patients with short tear film break-up time-type dry eye disease

Changes after treatment

Age of patients (mean ± SD)

p value

Improved

Not improved

Subjective dry eye symptom

53.4 ± 27.5

63.3 ± 13.9

0.012

Tear film break-up timea

55.5 ± 13.8

56.5 ± 14.5

0.782

Ocular staining score

54.6 ± 13.9

57.8 ± 14.1

0.359

  1. aAn increase in tear film break-up time after treatment was defined as “Improved, and a decrease as “Worsened”. The same values of tear film break-up time before and after treatment were defined as “No change