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Table 3 The age of patients who showed improvement in dry eye symptoms and ocular signs after 4 weeks of topical 3% diquafosol ophthalmic solution administration

From: Therapeutic effects of 3% diquafosol ophthalmic solution in patients with short tear film break-up time-type dry eye disease

Changes after treatment Age of patients (mean ± SD) p value
Improved Not improved
Subjective dry eye symptom 53.4 ± 27.5 63.3 ± 13.9 0.012
Tear film break-up timea 55.5 ± 13.8 56.5 ± 14.5 0.782
Ocular staining score 54.6 ± 13.9 57.8 ± 14.1 0.359
  1. aAn increase in tear film break-up time after treatment was defined as “Improved, and a decrease as “Worsened”. The same values of tear film break-up time before and after treatment were defined as “No change