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Table 3 Haplotype analysis of the target genes in PACG and control cohorts

From: Association of Genes implicated in primary angle-closure Glaucoma and the ocular biometric parameters of anterior chamber depth and axial length in a northern Chinese population

Block

SNPS

Haplotype

Freq of cases (%)

Freq of controls (%)

OR

P-value

Block 1

rs2179129, rs4823006, rs3178915

AGA

41.77

38.74

1.15

0.153

AGG

6.92

6.54

1.15

0.476

GAG

40.29

42.48

0.924

0.403

AAG

10.69

10.48

0.96

0.785

Block 2

rs5745718, rs12536657, rs12540393, rs17427817

TACC

13.81

13.09

0.926

0.575

GGCC

3.02

2.02

0.961

0.895

GGTG

82.25

84.26

1.05

0.687

Block 3

rs2510143, rs36015759

GA

24.18

23.35

1.1

0.396

AG

13.48

15.41

0.857

0.251

GG

62.12

61.05

1.01

0.907

  1. OR and P-value were calculated with the logistic regression model by adjusting for age and sex
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BMC Ophthalmology

ISSN: 1471-2415

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