Fig. 3

TUNEL-positive cells in the RGC layer and the density of RGC in the retinas. a, c In the sham group, the densities of RGCs were 3075 ± 298 /mm2 and 2615 ± 138 /mm2 in the central and midperipheral retinas, respectively. And in the photodynamic group, the densities of RGCs were 2078 ± 141 /mm2 and 1691 ± 142 /mm2 in the central and midperipheral retinas, respectively. **p < 0.01 compared with the sham group in the central and midperipheral retinas (N = 6 in each group, Bar = 50 um). b, d At the sham group, bits of TUNEL-positive cells in the RGC layer (1.4 ± 0.55 cells) were detected. At the AION group, the number of TUNEL-positive cells significantly inscreased and reached a peak (5.71 ± 0.76 cells) (**P < 0.01 compared with the sham group, N = 6 in each group; field of 200× 200 μm)