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Fig. 3 | BMC Ophthalmology

Fig. 3

From: Complete regression of branching vascular network in polypoidal choroidal vasculopathy by ranibizumab and photodynamic therapy, two case reports

Fig. 3

En face optical coherence tomography angiography and corresponding cross-sectional optical coherence tomography angiography with flow signals of polypoidal choroidal vasculopathy in case 1. Just before combination therapy of intravitreal injection of ranibizumab (IVR) and photodynamic therapy (PDT), en face optical coherence tomography angiography (OCT-A) shows the branching vascular network (BVN, blue arrows) and a polyp (yellow arrow) (a). Cross-sectional OCT-A on the plane of the white line in (a) shows pigment epithelium detachment (PED) containing a total of 3 flow signals that correspond to the BVN (2 blue arrows) and polyp (yellow arrow) (b). OCT-A at 1 week after PDT shows complete regression of both the BVN and polyp (c), which can be confirmed in cross-sectional OCT-A that does not show any flow signals in the mildly flattened PED (d). Three months after PDT, the BVN has restored most of its original network (blue arrows) observed in (a) while the polyp remains absent (yellow arrow) (e). In cross-sectional OCT-A at 3 months, 2 flow signals that correspond to the restored branches of the BVN are present (blue arrows) and flow signals for the polyp are missing (f)

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