Fig. 3

Photomicrograph of a cross section of temporal artery shows (a) almost total occlusion of the vascular lumen (arrow) due to fibrointimal proliferation and arteritis (Hematoxylin and eosin stain; original magnification × 100.). b Infiltration of the arterial intima and media by patchy moderately dense lymphohistiocytic inflammatory cells (arrows). The arterial lumen is reduced to a narrow slit-like channel (arrowhead)(Hematoxylin and eosin stain; original magnification × 200.) c High magnification shows mononuclear inflammatory cell infiltrate mixed with scattered multinucleated giant cells (arrowhead) in the vessel wall. Fragmentation of the internal elastic lamina (arrow) and fibrointimal proliferation and edema (curved arrow) of the arterial intima is also shown (Hematoxylin and eosin stain; original magnification × 400.) d High magnification shows a lymphohistiocytic inflammatory cell infiltrate (arrowhead) destroying and disrupting the internal elastic lamina (arrow). (Hematoxylin and eosin stain; original magnification × 400.) Inset: shows elastic tissue stain highlighting the fragmented internal elastic lamina (arrowhead). (Elastic Van Gieson stain; original magnification × 400