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Fig. 6 | BMC Ophthalmology

Fig. 6

From: Mitochondria-targeted antioxidant SKQ1 protects cornea from oxidative damage induced by ultraviolet irradiation and mechanical injury

Fig. 6

Morphology of cornea after trephine scarification upon treatment with SkQ1. Representative microscopic images of hematoxylin and eosin staining of normal rabbit cornea (a) or rabbit corneas scarified with trephine knife (7 mm in diameter, 50 μm deep) (B-G). Corneas without treatment on the 1st (b), 3rd (c) and 4th (d) day after trephination. Corneas treated with daily instillations of 7.5 μM SkQ1 on the 1st (e), 3rd (f) and 4the (g) day after trephination. Ep - corneal epithelium (if the designation Ep is absent, a complete loss of corneal epithelium is observed in preparation), Str - stroma, DM - Descemet’s membrane. Green arrowhead labels margin of migrating activated epithelial roll. Green arrows are for activated collagen-synthesizing keratocytes. Granulocytic infiltration in stroma and anterior eye chamber is shown by red arrows. Due to abundance of granulocytes and activated keratocytes, not every one of them is labeled). Magnification ✕200, scale bar 100 μm

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