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Table 3 Mean vessel density and retinal thickness measured in OCT angiography of all the patients

From: Macular evaluation of the retinal and choroidal vasculature changes in anterior ischemic optic neuropathy-a case control study

OCTA Parameters

Healthy

Uninvolved eyes

NAION eyes

P Value

(n = 27)

(n = 30)

(n = 37)

SVD (%)

 Whole

54.50 ± 1.34

50.55 ± 3.27

44.31 ± 5.35

p < 0.001*,†,‡,§

 Fovea

29.57 ± 1.68

25.40 ± 5.76

23.28 ± 5.08

p < 0.001*,†,‡

 Parafovea

56.57 ± 1.18

54.37 ± 3.13

48.76 ± 5.17

p < 0.001*,†,‡,§

 Superior-Hemi

56.37 ± 1.72

53.98 ± 3.55

48.72 ± 5.50

p < 0.001*,†,‡,§

 Inferior -Hemi

56.73 ± 1.51

54.74 ± 3.20

49.05 ± 5.07

p < 0.001*,†,‡,§

DVD (%)

 Whole

60.35 ± 1.12

60.08 ± 1.77

57.12 ± 2.48

p < 0.001*,‡,§

 Fovea

31.49 ± 2.21

30.36 ± 3.67

26.73 ± 2.70

p < 0.001*,‡,§

 Parafovea

62.08 ± 1.25

59.09 ± 1.97

54.36 ± 3.36

p < 0.001*,†,‡,§

 Superior-Hemi

61.82 ± 1.94

59.05 ± 2.23

54.87 ± 3.97

p < 0.001*,†,‡,§

 Inferior -Hemi

60.75 ± 2.23

59.13 ± 1.97

53.95 ± 3.80

p < 0.001*,†,‡,§

CVD (%)

 Whole

64.12 ± 0.95

63.94 ± 1.49

63.33 ± 1.27

p = 0.035*,‡

 Fovea

59.39 ± 1.94

58.78 ± 2.90

59.07 ± 4.09

p = 0.775*

 Parafovea

64.97 ± 1.34

65.68 ± 1.50

63.21 ± 2.26

p < 0.001*,‡,§

 Superior-Hemi

66.13 ± 1.65

65.64 ± 1.76

62.90 ± 2.34

p < 0.001*,‡,§

 Inferior -Hemi

65.56 ± 1.49

65.73 ± 1.59

63.15 ± 1.80

p < 0.001*,‡,§

Parafovea SRT (um)

111.89 ± 11.86

111.47 ± 12.14

96.43 ± 14.40

p < 0.001*,‡,§

Parafovea DRT (um)

193.04 ± 9.37

191.67 ± 12.31

183.32 ± 11.86

p = 0.001*,‡,§

  1. NAION Nonarteritic anterior ischemic optic neuropathy, OCT-A optical coherence tomography angiography, SVD superficial vessel density, DVD deep vessel density, CVD choroid vessel density, SRT superficial retinal thickness, DRT deep retinal thickness
  2. *Statistical significance tested by ANOVA for normal distributions and Kruskal–Wallis tests for nonnormal distributions; all comparisons were corrected with the post hoc test
  3. Significant difference between mean values of healthy eyes and uninvolved eyes
  4. Significant difference between mean values of healthy eyes and NAION eyes
  5. §Significant difference between mean values of uninvolved eyes and NAION eyes