Table 5 Diagnostic accuracy (AUROC) for OCT-A vessel density and RNFL thickness measurements in all the patients
Diagnostic parameters | Healthy eyes | Uninvolved eyes | NAION eyes | p Value | AUROC (SE) NAION vs. healthy Eyes | AUROC (SE) Uninvolved eyes vs. healthy Eyes |
|---|---|---|---|---|---|---|
(95% CI) | (95% CI) | (95% CI) | ||||
Average RNFL, um | 102.1 (99.6–105.1) | 98.9 (96.0–103.1) | 70.9 (67.7–74.1) | < 0.001*,†,‡ | 0.99 (0.01) | 0.68 (0.07) |
Parafovea SRT, um | 111.9 (107.7–115.8) | 111.5 (107.3–115.3) | 96.4 (92.3–101.0) | < 0.001*,†,‡ | 0.81 (0.05) | 0.50 (0.08) |
Parafovea DRT, um | 193.0 (189.5–197.3) | 191.7 (187.6–196.1) | 183.3 (179.7–187.3) | 0.001*,†,‡ | 0.73 (0.06) | 0.51 (0.08) |
OCT-A whole SVD,% | 54.5 (54.0–55.0) | 50.5 (49.5–51.8) | 44.3 (42.5–46.0) | < 0.001*,†,,‡§ | 0.96 (0.03) | 0.89 (0.05) |
OCT-A whole DVD,% | 60.3 (59.9–60.8) | 60.1 (59.6–60.6) | 57.1 (56.1–57.8) | < 0.001*,†,‡,§ | 0.89 (0.04) | 0.53 (0.08) |
OCT-A whole CVD,% | 64.1 (63.8–64.5) | 63.9 (63.4–64.5) | 63.3 (62.9–63.7) | 0.079 | 0.68 (0.07) | 0.53 (0.08) |