Skip to main content
Fig. 4 | BMC Ophthalmology

Fig. 4

From: All-trans retinoic acid stimulates the secretion of TGF-β2 via the phospholipase C but not the adenylyl cyclase signaling pathway in retinal pigment epithelium cells

Fig. 4

SQ22536 did not suppress the quantity of TGF-β2 protein induced by ATRA in the supernatants of D407 cells. TGF-β2 protein levels in conditioned media were measured by ELISA and normalized to cell counts (1 × 106). There was no significant difference in the secretion of TGF-β2 of the ATRA-treated group and SQ22536 (5–40 μM) + ATRA-treated group (p > 0.05). Data are represented as the mean ± SEM. Statistical comparisons were performed with one-way ANOVA. *Significance versus control group (p < 0.001; n = 3 per treatment). #Significance versus ATRA-treat group (10 μM) (p < 0.001; n = 3 per treatment)

Back to article page

BMC Ophthalmology

ISSN: 1471-2415

Contact us